Do Near-Infrared Intra-Operative Findings Obtained Using Indocyanine Green Correlate with Post-Thyroidectomy Parathyroid Function? the Icgpredict Study
Autor: | Dimitris Koutsoumparis, Angeliki Chorti, Stavros Panidis, Antonios Michalopoulos, Panagiotis Anagnostis, Ioannis Pliakos, Theodosios Papavramidis |
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Rok vydání: | 2020 |
Předmět: |
Indocyanine Green
medicine.medical_specialty Intra operative genetic structures Hypoparathyroidism Endocrinology Diabetes and Metabolism medicine.medical_treatment Urology Parathyroid hormone 030209 endocrinology & metabolism Parathyroid Glands 03 medical and health sciences chemistry.chemical_compound Postoperative Complications 0302 clinical medicine Endocrinology medicine Humans Prospective Studies 030212 general & internal medicine Prospective cohort study Surgical team business.industry Near-infrared spectroscopy Thyroid Thyroidectomy General Medicine medicine.disease medicine.anatomical_structure chemistry Parathyroid Hormone Nuclear medicine Complication business Indocyanine green |
Zdroj: | Endocrine Practice. 26:967-973 |
ISSN: | 1530-891X |
DOI: | 10.4158/ep-2020-0119 |
Popis: | Objective: Post-operative hypoparathyroidism still remains a significant complication after thyroidectomy. Intraoperative imaging modalities, such as near infrared fluorescence by the use of indocyanine green (ICG), may assist to identify and preserve the parathyroid glands (PGs). The purpose of this study was to test the association between intra-operative ICG staining scoring system and 24-h post-operative parathyroid hormone (PTH) levels, as well as its capability of intra-operative PG identification. Methods: This was a prospective study, recruiting patients scheduled for total thyroidectomy by the same surgical team, from December 2018 to April 2019. Intraoperative angiography was performed, after infusion of ICG solution (5 mg). Two minutes later, images were acquired by the near-infrared system. Results: Sixty patients fulfilled eligibility criteria. The percentage of temporary post-operative hypoPT (defined as PTH |
Databáze: | OpenAIRE |
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