The rs1143634 of IL-1$\beta$ gene is associated with external apical root resorption in Iranian population
| Autor: | Soudeh Ghafouri-Fard, Faezeh Javaheri, Mir Davood Omrani, Rezvan Noroozi, Mohammad Taheri, Hossein Mohammad-Rahimi, Mohammad Behnaz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
education.field_of_study ORTHODONTIC PROCEDURES business.industry Population Interleukin Dentistry Bone resorption Iranian population 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Genetics Medicine education business Complication Gene Apical root resorption Genetics (clinical) |
| Popis: | External apical root resorption (EARR) is a common iatrogenic problem caused by orthodontic intervention. Based on the role of Interleukin 1 (IL-1) in induction of bone reabsorption and activation of osteoclasts, this gene is a candidate for predisposition to this complication. Here, we genotyped the rs1143634 in the IL-1β and rs1800587 in the IL-1α gene in a population of Iranian patients who received orthodontic procedures. Patients were classified into two groups: EARR cases (58 individuals) who had a minimum of 1 maxillary incisor with EARR≥2 mm, and the control group (82 individuals), with EARR |
| Databáze: | OpenAIRE |
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