Applications of Ring Closing Metathesis. Total Synthesis of (±)-Pseudotabersonine†
| Autor: | James D. Sunderhaus, Bo Cheng, Stephen F. Martin |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Popis: | A novel approach to the Aspidosperma family of alkaloids was developed and applied to a concise total synthesis of (±)-pseudotabersonine that was accomplished in 11 steps. Key transformations include a stepwise variant of a Mannich-like multicomponent assembly process, a double ring-closing metathesis sequence, and a one-pot deprotection/cyclization reaction. |
| Databáze: | OpenAIRE |
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