Adding wisdom to ‘smart’ bioelectronic systems: a design framework for physiologic control including practical examples

Autor: Phil Starr, Gregory A. Worrell, Timothy J. Denison, Kent Leyde, Vaclav Kremen, Enrico Opri, Aysegul Gunduz, Roee Gilron
Rok vydání: 2019
Předmět:
Zdroj: Europe PubMed Central
Bioelectronics in medicine
Popis: This perspective provides an overview of how risk can be effectively considered in physiological control loops that strive for semi-to-fully automated operation. The perspective first introduces the motivation, user needs and framework for the design of a physiological closed-loop controller. Then, we discuss specific risk areas and use examples from historical medical devices to illustrate the key concepts. Finally, we provide a design overview of an adaptive bidirectional brain–machine interface, currently undergoing human clinical studies, to synthesize the design principles in an exemplar application.
Databáze: OpenAIRE