The use of iloprost in the treatment of ‘out of proportion’ pulmonary hypertension in chronic obstructive pulmonary disease
| Autor: | Bartosz Lasota, Szymon Skoczyński, Władysław Pierzchała, Katarzyna Mizia-Stec |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Hypertension Pulmonary Vasodilator Agents Pharmaceutical Science Case Report Heart failure Blood Pressure Pharmacy Prostanoids Toxicology Pulmonary function testing Pulmonary hypertension Pulmonary Disease Chronic Obstructive medicine.artery Internal medicine medicine Humans Pharmacology (medical) Iloprost Pharmacology Inhalation business.industry Chronic obstructive pulmonary disease Respiratory disease medicine.disease Blood pressure Treatment Outcome Pulmonary artery Cardiology cardiovascular system business medicine.drug |
| Zdroj: | International Journal of Clinical Pharmacy |
| ISSN: | 2210-7711 2210-7703 |
| Popis: | Case Pulmonary hypertension secondary to respiratory disease most often occurs as a complication of chronic obstructive pulmonary disease, which currently constitutes one of the leading causes of death. Some patients with hypoxaemia reveal “out of proportion” pulmonary hypertension with inappropriate increase of pulmonary artery pressure. Iloprost, analogue of prostacyclin, dilates systemic vessels and pulmonary vessels in particular if administered by inhalation. It appears to be important, life-saving, complementary therapy. However, there is no evidence for its routine use in out of proportion arterial pulmonary hypertension. This case study presents a 44-year old man with chronic obstructive pulmonary disease and “out of proportion” pulmonary hypertension. We present the results of his treatment with iloprost. Conclusion In a patient with “out of proportion” pulmonary hypertension due to chronic obstructive pulmonary disease, inhaled iloprost led to improvement in clinical status and echocardiographic parameters, including a reduction of right ventricular systolic pressure. |
| Databáze: | OpenAIRE |
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