Mild Acquired Factor XIII Deficiency and Clinical Relevance at the ICU—A Retrospective Analysis
| Autor: | S. Alesci, Markus A. Weigand, Sebastian Casu, Wolfgang Miesbach, Maik von der Forst, Felix Carl Fabian Schmitt |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Blood transfusion Adolescent medicine.medical_treatment Acquired Factor XIII Deficiency Original Manuscript 030204 cardiovascular system & hematology blood transfusion blood coagulation 03 medical and health sciences Young Adult 0302 clinical medicine medicine Coagulopathy Diseases of the circulatory (Cardiovascular) system Humans Clinical significance Aged Retrospective Studies Aged 80 and over business.industry Incidence (epidemiology) factor XIII Hematology General Medicine Perioperative Middle Aged Factor XIII medicine.disease Factor XIII Deficiency critical care RC666-701 Female hemorrhage Complication business 030215 immunology medicine.drug |
| Zdroj: | Clinical and Applied Thrombosis/Hemostasis Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021) |
| ISSN: | 1938-2723 1076-0296 |
| Popis: | Acquired FXIII deficiency is a relevant complication in the perioperative setting; however, we still have little evidence about the incidence and management of this rarely isolated coagulopathy. This study aims to help find the right value for the substitution of patients with an acquired mild FXIII deficiency. In this retrospective single-center cohort study, we enrolled critically ill patients with mild acquired FXIII deficiency (>5% and ≤70%) and compared clinical and laboratory parameters, as well as pro-coagulatory treatments. The results of the present analysis of 104 patients support the clinical relevance of FXIII activity out of the normal range. Patients with lower FXIII levels, beginning at |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|