Long-term exposure to virgin and seawater exposed microplastic enriched-diet causes liver oxidative stress and inflammation in gilthead seabream Sparus aurata, Linnaeus 1758
| Autor: | X. Capó, J.J. Company, C. Alomar, M. Compa, A. Sureda, A. Grau, B. Hansjosten, J. López-Vázquez, J.B. Quintana, R. Rodil, S. Deudero |
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| Přispěvatelé: | Universidade de Santiago de Compostela. Departamento de Química Analítica, Nutrición e Bromatoloxía, Universidade de Santiago de Compostela. Instituto de Investigación e Análises Alimentarias |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Environmental Engineering
Antioxidant 010504 meteorology & atmospheric sciences medicine.medical_treatment Microplastics Glutathione reductase sea water islands 010501 environmental sciences medicine.disease_cause liver 01 natural sciences Investigación::23 Química::2301 química analítica ::230102 Análisis bioquímico [Materias] Andrology Superoxide dismutase chemistry.chemical_compound Centro Oceanográfico de Baleares Sparus aurata medicine Animals Environmental Chemistry Ingestion Seawater Medio Marino Waste Management and Disposal Ecosystem 0105 earth and related environmental sciences chemistry.chemical_classification fish Inflammation research biology Chemistry Glutathione peroxidase Catalase Malondialdehyde Pollution Sea Bream Diet Oxidative stress biology.protein Plastics Water Pollutants Chemical |
| Zdroj: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela instname e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela Universidad de Santiago de Compostela (USC) |
| Popis: | Plastics accumulation in marine ecosystems has notable ecological implications due to their long persistence, potential ecotoxicity, and ability to adsorb other pollutants or act as vectors of pathogens. The present work aimed to evaluate the physiological response of the gilthead seabream (Sparus aurata) fed for 90 days with a diet enriched with virgin and seawater exposed low-density polyethylene microplastics (LDPE-MPs) (size between 100 and 500 μM), followed by 30 days of depuration, applying oxidative stress and inflammatory markers in liver homogenates. No effects of LDPE-MPs treatments on fish growth were observed throughout this study. A progressive increase in antioxidant enzyme activities was observed throughout the study in both treatments, although this increase was higher in the group treated with seawater exposedMPs. This increase was significantly higher in catalase (CAT), glutathione reductase (GRd), and glutathione-s-transferase (GST) in the seawater exposedMPs group, with respect to the virgin group. In contrast, no significant differenceswere recorded in superoxide dismutase (SOD) and glutathione peroxidase (GPx) between both groups. Exposure to MPs also caused an increase in the oxidative damage markers (malondialdehyde and carbonyls groups). Myeloperoxidase activity significantly increased because of MPs treatments. After 30 days of depuration, antioxidant, inflammatory enzyme activities and oxidative damage markers returned to values similar to those observed in the control SI |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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