Effects of persistent perilymph fistula on the inner ear
| Autor: | Toru Suzuki, Yumiko Kaseki, Tsutomu Nakashima, Noriyuki Yanagita, Shigeji Fukuta |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Fistula
Hearing loss Cochlear Diseases Hearing Loss Sensorineural Guinea Pigs Perilymph otorhinolaryngologic diseases Medicine Animals Inner ear Organ of Corti Cochlea Hair Cells Auditory Inner business.industry Blood flow Anatomy Vestibular Function Tests medicine.disease Cannula Microspheres medicine.anatomical_structure Otorhinolaryngology Round Window Ear sense organs Hair cell medicine.symptom business |
| Zdroj: | The Laryngoscope. 101(10) |
| ISSN: | 0023-852X |
| Popis: | To study the effects of a persistent perilymph fistula on the cochlea, a small cannula was inserted into the scala tympani of the basal turn of cochlea in guinea pigs. A month later, cochlear morphology and blood flow were studied using either histological evaluation or the microsphere surface preparation technique. Some animals showed no cochlear morphologic changes or no cochlear blood-flow reduction, even if tubal patency was maintained and perilymph leakage lasted for 1 month. This suggests that a prolonged perilymph fistula, per se, causes no permanent cochlear damage. However, in some animals, hair cell damage and cochlear blood-flow disorders were observed. These observations and the causes of hearing loss in clinical cases of perilymph fistula were studied. |
| Databáze: | OpenAIRE |
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