Evaluation of genotoxicity from Nilufer Stream (Bursa/Turkey) water using piscine micronucleus test

Autor: Senay Summak, Dilek Yilmaz, Rahmi Bilaloglu, Tolga Zorlu, Nilüfer Aydemir, Ozgur Vatan
Přispěvatelé: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., Summak, Şenay, Çinkılıç, Nilüfer, Vatan, Özgür, Yılmaz, Dilek, Zorlu, Tolga, Bilaloğlu, Rahmi, O-7508-2015, AAH-5296-2021
Rok vydání: 2010
Předmět:
Nuclear abnormalities
Chromium
Cytoplasm
Erythrocytes
Aquatic environments
Turkey
Micronucleus tests
Nitrate
Toxicology
medicine.disease_cause
In situ
Turkey(republic)
Water supply
Dissolved oxygen
In vivo study
Mutagenicity
Nickel
Fish micronuclei
Chemical analysis
Water pollutant
Water pollution
Nitrogen dioxide
River
Domestic waste
pH
Ecology
Biochemical oxygen demand
Oreochromis niloticus
Oreochromis niloticus (nile tilapia)
Environmental monitoring
Cichlids
Water sampling
General Medicine
Industrial waste
Pollution
Erythrocyte
Zinc
Oreochromis
Heavy metal
Water quality
Wastewater
Ultrastructure
Heavy-metals
Environmental chemistry
Micronucleus test
Mutagenic agent
Water temperature
Cichlid
Pisces
Cell damage
Animal cell
Water contamination
Cadmium
Stream (river)
Iron
Hydrogen-ion concentration
Chemical
Industrialization
Biology
Food science & technology
Fish-hoplias malabaricus
Comet Assay
Micronucleus Tests
Genotoxicity
Article
Water pollutants
Ammonia
Genetics
medicine
Animals
Comet assay
Nilufer Stream
Multinuclear cell
Pollutant
Drug effects
Toxicity
Animal
Urbanization
Nonhuman
biology.organism_classification
Metals
heavy
Oxygen
Fish
Lead
Cell nucleus
Micronucleus
Controlled study
Water Pollutants
Chemical
Biomarkers
Copper
Analysis
Mutagens
Aluminum
Food Science
Zdroj: Food and Chemical Toxicology. 48:2443-2447
ISSN: 0278-6915
Popis: In the present study, the in vivo micronucleus (MN) test in fish erythrocytes was used to evaluate the genotoxic potentials of water samples collected from four different sites along the Nilufer Stream which empties into the Marmara Sea on the north-west of Turkey. Nilufer Stream receives discharges of industrial and domestic wastes resulting from industrialization and urbanization activities in Bursa city. Nile tilapias (Oreochromis niloticus) were exposed to collected water samples under laboratory conditions for 3 and 6 days. Micronuclei analyses were carried out in peripheral blood erythrocytes. In addition to micronuclei, other nuclear abnormalities (NAs) such as bi-nucleated cells and binuclei with nucleoplasmic bridge and cells with blebbed, notched and lobbed nuclei, were assessed in the erythrocytes. Chemical analyses were also carried out in the water samples to assess the presence of major pollutants. MN and NA frequencies were significantly elevated in fishes exposed to water from polluted areas compared to those exposed to clean water sample. The results of this study indicate that Nilufer Stream is contaminated with potential genotoxic chemicals and the genotoxicity is possibly related with the industrial, agricultural and domestic activities.
Databáze: OpenAIRE
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