Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
| Autor: | Jaime A. Ramos, Rita Saraiva, Sara Santos, Joana Saiote, Verónica Gamelas, Guilherme Simões |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
tofacitinib Tofacitinib business.industry Gastroenterology Acute severe ulcerative colitis medicine.disease Ulcerative colitis Clinical Case Study acute severe ulcerative colitis Internal medicine medicine General Earth and Planetary Sciences lcsh:Diseases of the digestive system. Gastroenterology lcsh:RC799-869 business General Environmental Science |
| Zdroj: | GE Port J Gastroenterol GE-Portuguese Journal of Gastroenterology v.29 n.2 2022 GE: Portuguese Journal of Gastroenterology, Pp 1-3 (2021) |
| ISSN: | 2387-1954 2341-4545 |
| DOI: | 10.1159/000514781 |
| Popis: | Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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