Ewing’s Sarcoma of the Vertebral Body in an Adolescent: A Rare Case Report and Literature Review
| Autor: | Faris Aiman Sarifulnizam, Husna Mohd Apandi, Mohd Yazid Bajuri, Mohamad Fauzlie Yusof, Teik Chiang Goh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Cord 030204 cardiovascular system & hematology Malignancy Pediatrics Lesion 03 medical and health sciences 0302 clinical medicine paraplegia Spinal cord compression spinal cord compression medicine Back pain ewing's sarcoma business.industry General Engineering Ewing's sarcoma medicine.disease Vertebra Surgery medicine.anatomical_structure Orthopedics Oncology medicine.symptom business Paraplegia primary spine tumour 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | We report the case of a 14-year-old girl who presented with a one-month history of back pain and bilateral lower limb weakness preceded by constitutional symptoms. She neither had a family history of malignancy nor a previous history of trauma. A series of imaging procedures revealed an aggressive lesion of the T12 vertebra with a large soft-tissue component and intraspinal extension leading to spinal cord compression causing cord edema. She underwent urgent posterior instrumentation and fixation of T9 to T12 vertebrae due to worsening neurological deficits. Adjuvant and neoadjuvant chemotherapy with palliative spinal stabilisation were also performed. Features of the lesion were highly consistent with ES on immunohistochemical study and fluorescence in situ hybridization (FISH) analysis for the EWSR1 gene. Postoperatively, both of her lower limbs improved in power and she benefited from regular physiotherapy. |
| Databáze: | OpenAIRE |
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