Synthesis and Rhodium(II)-Mediated Cascade Cyclopropanation/Rearrangement/Isomerization of Diazo 2,3,5-Trisubstituted Furans: The Construction of Penta-substituted Aromatic Compounds
Autor: | Jianbo Wang, Guisheng Deng, Qin Yang, Jianfang Zhang, Yang Zhu |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | The Journal of Organic Chemistry. 85:2395-2405 |
ISSN: | 1520-6904 0022-3263 |
Popis: | Ag(I)-catalyzed synthesis of diazo-trisubstituted furans starting from diazo-cumulated allenyl ketones has been investigated. The Rh2(OAc)4-catalyzed reaction of the diazo 2,3,5-trisubstituted furans provided penta-substituted aromatics via cascade intermolecular cyclopropanation/rearrangement/isomerization. The cyclopropanation on the furan ring/rearrangement of cyclopropane moiety has been reported. A reasonable mechanism is proposed. |
Databáze: | OpenAIRE |
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