Anticoagulant therapy with a purified fraction of Malayan pit viper venom
| Autor: | A.M. Paxton, B.A. Warren, M.J. Allington, A.A. Sharp |
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| Rok vydání: | 1968 |
| Předmět: |
Ancrod
Adult Blood Platelets Male medicine.medical_specialty Dilute Russell's viper venom time Adolescent Venom Hemorrhage Pharmacology Injections Intramuscular Fibrin medicine Malayan pit viper Humans In patient Aged biology business.industry Antivenins Venoms Fibrinolysis Fibrinogen Thrombosis General Medicine Middle Aged Thrombophlebitis medicine.disease Surgery Blood Cell Count Venous thrombosis Anticoagulant therapy Injections Intravenous biology.protein Female Blood Coagulation Tests business medicine.drug |
| Zdroj: | Lancet (London, England). 1(7541) |
| ISSN: | 0140-6736 |
| Popis: | Anticoagulant therapy has been carried out by producing defibrination in nineteen patients by means of a purified coagulant fraction ('Arvin') derived from the venom of the Malayan pit viper ( Agkistrodon rhodostoma ). Complete defibrination has been achieved rapidly by small amounts of this material given intravenously or intramuscularly and it has been possible to maintain this situation by injections at intervals for periods up to 3 weeks. The results obtained using this form of anticoagulant therapy in patients with venous thrombosis suggest that a more comprehensive trial of this agent is justified. |
| Databáze: | OpenAIRE |
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