What is the effect of spinal manipulation on the pressure pain threshold in young, asymptomatic subjects? A randomized placebo-controlled trial, with a cross-over design
| Autor: | Niels Wedderkopp, Olivier Gagey, Mathieu Picchiottino, Margaux Honoré, Charlotte Leboeuf-Yde |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
lcsh:Diseases of the musculoskeletal system Placebo-controlled study Manipulation vertébrale law.invention Placebos 0302 clinical medicine Randomized controlled trial law Surveys and Questionnaires Medicine Single-Blind Method 030212 general & internal medicine Effet education.field_of_study Cross-Over Studies Chiropractic Healthy Volunteers Anesthesia Durée Spinal manipulation Female medicine.symptom Adult Manipulation Spinal Pain Threshold Adolescent Population Seuil de douleur de pression Physical Therapy Sports Therapy and Rehabilitation Effect size Asymptomatic Young Adult 03 medical and health sciences Sham Statistical significance Humans Essai contrôlé randomisé Placébo Effect education Asymptomatic subjects Pressure pain threshold business.industry Research lcsh:Chiropractic Crossover study Taille de l’effet Duration Complementary and alternative medicine lcsh:RZ201-275 Sujets asymptomatiques Chiropractics lcsh:RC925-935 business 030217 neurology & neurosurgery |
| Zdroj: | Chiropractic & Manual Therapies, Vol 28, Iss 1, Pp 1-10 (2020) Honoré, M, Picchiottino, M, Wedderkopp, N, Leboeuf-Yde, C & Gagey, O 2020, ' What is the effect of spinal manipulation on the pressure pain threshold in young, asymptomatic subjects? A randomized placebo-controlled trial, with a cross-over design ', Chiropractic & Manual Therapies, vol. 28, 6 . https://doi.org/10.1186/s12998-020-0296-1 Chiropractic & Manual Therapies |
| DOI: | 10.1186/s12998-020-0296-1 |
| Popis: | Background Spinal manipulation (SM) has been shown to have an effect on the pressure pain threshold (PPT) in asymptomatic subjects, but SM has never been compared in studies on this topic to a validated sham procedure. We investigated the effect of SM on the PPT when measured i) in the area of intervention and ii) in an area remote from the intervention. In addition, we measured the size and duration of the effect. Method In a randomized cross-over trial, 50 asymptomatic chiropractic students had their PPT measured at baseline, immediately after and every 12 min after intervention, over a period of 45 min, comparing values after SM and a previously validated sham. The trial was conducted during two sessions, separated by 48 h. PPT was measured both regionally and remotely from the ‘treated’ thoracic segment. Blinding of study subjects was tested with a post-intervention questionnaire. We used mixed linear regression with the baseline value and time as co-variates. If a significant difference were found between groups, then an effect size would be calculated using Cohen’s d or Hedge’s h coefficient. Statistical significance was set at p Results Study subjects had been successfully blinded. No statistically significant differences were found between SM and sham estimates, at any time or anatomical location. Conclusion When compared to a valid sham procedure and with successfully blinded subjects, there is no regional or remote effect of spinal manipulation of the thoracic spine on the pressure pain threshold in a young pain-free population. |
| Databáze: | OpenAIRE |
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