Myoclonic spasms during treatment with high doses of intravenous morphine in renal failure

Autor: L. Dragsted, C. B. Christensen, P. Sjøgren
Rok vydání: 1993
Předmět:
Zdroj: Acta Anaesthesiologica Scandinavica. 37:780-782
ISSN: 1399-6576
0001-5172
DOI: 10.1111/j.1399-6576.1993.tb03809.x
Popis: Myoclonic spasms occurred in a patient suffering from renal failure after high doses of continuous intravenous morphine (100 mg/h). The concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide (mumol/l) in plasma were: 1.93, 52.06 and 381.8, and in cerebrospinal fluid were: 1.02, 5.86 and 61.82, respectively. The role of morphine and morphine glucuronides in myoclonic spasms is discussed.
Databáze: OpenAIRE