Laterality of temporoparietal causal connectivity during the prestimulus period correlates with phonological decoding task performance in dyslexic and typical readers
| Autor: | Janet McGraw Fisher, Richard E. Frye, Jacqueline Liederman, Meng-Hung Wu |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male magnetoencephalography effective connectivity Cognitive Neuroscience media_common.quotation_subject Network structure 050105 experimental psychology Functional Laterality Task (project management) Dyslexia 03 medical and health sciences Cellular and Molecular Neuroscience Young Adult 0302 clinical medicine Reading (process) Image Interpretation Computer-Assisted Neural Pathways Task Performance and Analysis medicine Humans 0501 psychology and cognitive sciences media_common Brain Mapping 05 social sciences Phonology Articles medicine.disease Magnetic Resonance Imaging Reading Laterality Granger causality Female Psychology 030217 neurology & neurosurgery Decoding methods Cognitive psychology |
| Zdroj: | Cerebral Cortex (New York, NY) |
| ISSN: | 1460-2199 |
| Popis: | We examined how effective connectivity into and out of the left and right temporoparietal areas (TPAs) to/from other key cortical areas affected phonological decoding in 7 dyslexic readers (DRs) and 10 typical readers (TRs) who were young adults. Granger causality was used to compute the effective connectivity of the preparatory network 500 ms prior to presentation of nonwords that required phonological decoding. Neuromagnetic activity was analyzed within the low, medium, and high beta and gamma subbands. A mixed-model analysis determined whether connectivity to or from the left and right TPAs differed across connectivity direction (in vs. out), brain areas (right and left inferior frontal and ventral occipital–temporal and the contralateral TPA), reading group (DR vs. TR), and/or task performance. Within the low beta subband, better performance was associated with increased influence of the left TPA on other brain areas across both reading groups and poorer performance was associated with increased influence of the right TPA on other brain areas for DRs only. DRs were also found to have an increase in high gamma connectivity between the left TPA and other brain areas. This study suggests that hierarchal network structure rather than connectivity per se is important in determining phonological decoding performance. |
| Databáze: | OpenAIRE |
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