Vancomycin Induced Thrombocytopenia – Protracted Course in a Hemodialysis Patient
| Autor: | Sindhu Priya Devarashetty, Samip Master, Nisha Ajit |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Side effect medicine.medical_treatment Drug induced thrombocytopenia Case Report lcsh:RC254-282 End stage renal disease 03 medical and health sciences Protracted course 0302 clinical medicine Vancomycin hemic and lymphatic diseases medicine In patient business.industry Bleed biochemical phenomena metabolism and nutrition lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens 030104 developmental biology Oncology 030220 oncology & carcinogenesis Anesthesia Platelet destruction Hemodialysis business medicine.drug |
| Zdroj: | Case Reports in Oncology Case Reports in Oncology, Vol 12, Iss 3, Pp 749-754 (2019) |
| ISSN: | 1662-6575 |
| Popis: | Vancomycin induced thrombocytopenia (VIT) is an uncommon side effect of vancomycin which can manifest from mild petechiae to life-threatening bleed. Decreased renal clearance of vancomycin results in prolonged thrombocytopenia by antibody-mediated platelet destruction in the presence of vancomycin. Improvement in thrombocytopenia is achieved with the elimination of vancomycin. We describe a patient with end stage renal disease who experienced a protracted course of thrombocytopenia from vancomycin. We illustrate the mechanism of thrombocytopenia and the treatment modalities used by us and those described in literature. VIT is an important differential in patients with thrombocytopenia admitted to the hospital. |
| Databáze: | OpenAIRE |
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