Systemic chemotherapy for carcinoma of the cervix
| Autor: | Saul W. Soffar, Julian P. Smith, Felix N. Rutledge, Beaury C. Burns |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
Adult
Oncology Subjective response medicine.medical_specialty Cyclophosphamide medicine.medical_treatment Uterine Cervical Neoplasms Antineoplastic Agents Adenocarcinoma Internal medicine medicine Carcinoma Humans Hydroxyurea Urea Mechlorethamine Neoplasm Metastasis Melphalan Cervix Objective response Aged Chemotherapy Systemic chemotherapy business.industry Obstetrics and Gynecology Middle Aged medicine.disease Methotrexate medicine.anatomical_structure Carcinoma Squamous Cell Female Fluorouracil Neoplasm Recurrence Local Progestins business Thiotepa medicine.drug Disseminated Carcinoma |
| Zdroj: | American Journal of Obstetrics and Gynecology. 97:800-807 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(67)90614-x |
| Popis: | Of 107 patients with recurrent or disseminated carcinoma of the cervix, 19 per cent obtained an objective response to an alkylating agent administered systemically, and 31 per cent obtained a subjective response. Patients who obtain a response to chemotherapy survive approximately 4 months longer than those who fail to do so. Whether a carcinoma of the cervix will respond to a chemotherapeutic agent cannot be determined from the age or race of the patient, or the histologic appearance of the original tumor. Cyclophosphamide is the safest and most easily administered of the chemotherapeutic agents we have employed for recurrent or disseminated carcinoma of the cervix. |
| Databáze: | OpenAIRE |
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