Impact of renal function on residual platelet reactivity and clinical outcomes in patients with acute coronary syndrome treated with clopidogrel

Autor:	Luyao Yu, Jingang Zheng, Ying Liu, Yihong Sun, Yinong Chen, Qing Li
Rok vydání:	2021
Předmět:	Blood Platelets Ticagrelor medicine.medical_specialty Acute coronary syndrome Ticlopidine Platelet Aggregation Clinical Investigations Renal function 030204 cardiovascular system & hematology Kidney urologic and male genital diseases acute coronary syndrome 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Aspirin medicine.diagnostic_test business.industry Area under the curve thromboelastography General Medicine medicine.disease Clopidogrel Comorbidity female genital diseases and pregnancy complications Thromboelastography Cardiology high residual platelet reactivity Cardiology and Cardiovascular Medicine business chronic kidney disease Platelet Aggregation Inhibitors Kidney disease medicine.drug
Zdroj:	Clinical Cardiology
ISSN:	1932-8737 0160-9289
DOI:	10.1002/clc.23588
Popis:	Background Chronic kidney disease (CKD) is a common comorbidity in patients with acute coronary syndrome (ACS) and may potentially influence platelet function. Hypothesis We explored the influence of renal function on platelet reactivity to investigate whether high residual platelet reactivity (HRPR) is associated with cardiovascular events. Methods ACS patients treated with aspirin and clopidogrel were prospectively enrolled. Patients were categorized into two groups on the basis of baseline estimated glomerular filtration rate (eGFR): non‐CKD (eGFR ≥60 mL/min/1.73 m2) and CKD (eGFR
Databáze:	OpenAIRE
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