| Popis: |
Artificial Melanosome for Transdermal Delivery In article number 2103503 by Uk‐Jae Lee, Nathaniel S. Hwang, Byung‐Gee Kim, and co‐workers, light‐triggered in situ biosynthesis of artificial melanin in native skin is proposed and demonstrated using photoactivatable tyrosinase. Photoactivatable tyrosinase is synthesized with site‐specific incorporation of o‐nitrobenzyl tyrosine and then encapsulated into lipid nanoparticles as an artificial melanosome for transdermal delivery. This biomimetic system can recapitulate the biosynthetic analogs of naturally occurring melanin. [Image: see text] |
