Zinc-Based Biomaterials for Regeneration and Therapy
| Autor: | Yadong Wang, Yi-Xian Qin, Yingchao Su, Irsalan Cockerill, Yufeng Zheng, Lingqian Chang, Donghui Zhu |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Materials science Biocompatibility Cancer therapy chemistry.chemical_element Bioengineering Nanotechnology Biocompatible Materials 02 engineering and technology Zinc Regenerative Medicine Article Nanomaterials 03 medical and health sciences Tissue engineering Regeneration Regeneration (biology) 021001 nanoscience & nanotechnology Biometal Trace Elements 030104 developmental biology chemistry Drug delivery 0210 nano-technology Biotechnology |
| Zdroj: | Trends in biotechnology. 37(4) |
| ISSN: | 1879-3096 |
| Popis: | Zinc has been described as the 'calcium of the twenty-first century'. Zinc-based degradable biomaterials have recently emerged thanks to their intrinsic physiological relevance, biocompatibility, biodegradability, and pro-regeneration properties. Zinc-based biomaterials mainly include: metallic zinc alloys, zinc ceramic nanomaterials, and zinc metal-organic frameworks (MOFs). Metallic zinc implants degrade at a desirable rate, matching the healing pace of local tissues, and stimulating remodeling and formation of new tissues. Zinc ceramic nanomaterials are also beneficial for tissue engineering and therapy thanks to their nanostructures and antibacterial properties. MOFs have large surface areas and are easily functionalized, making them ideal for drug delivery and cancer therapy. This review highlights recent developments in zinc-based biomaterials, discusses obstacles to overcome, and pinpoints directions for future research. |
| Databáze: | OpenAIRE |
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