Norepinephrine-Induced Peripheral Ischemia Leading to Gangrene: A Case Series
| Autor: | Eric Goldschmidt, Kristin Schafer, Richard Simman, Michael Wilson, Benita Wu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Necrosis Dermatology Norepinephrine (medication) Gangrene 030207 dermatology & venereal diseases 03 medical and health sciences Norepinephrine 0302 clinical medicine Ischemia Acute care medicine Humans Vasoconstrictor Agents Adverse effect Aged Advanced and Specialized Nursing Peripheral Vascular Diseases business.industry 030208 emergency & critical care medicine Middle Aged medicine.disease Pathophysiology Peripheral Anesthesia Case-Control Studies Female medicine.symptom business Vasoconstriction medicine.drug |
| Zdroj: | Advances in skinwound care. 34(5) |
| ISSN: | 1538-8654 |
| Popis: | Norepinephrine is used in the acute care setting to establish and maintain hemodynamic stability in patients with hypotension. Although it is often a lifesaving medication, norepinephrine may lead to profound vascular insufficiency in the extremities, resulting in dry gangrene and skin necrosis. The purpose of this article is to present a case series of skin complications related to treatment with norepinephrine and review the pathophysiology behind these complications. The authors also explore risk stratification as it relates to history and clinical presentation with subsequent focus on contingencies to mitigate the adverse effects of vasoconstriction on peripheral tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|