Full-genome sequencing of a Hungarian canine G3P[3] Rotavirus A strain reveals high genetic relatedness with a historic Italian human strain
| Autor: | Vito Martella, Szilvia Marton, Szilvia L. Farkas, Giovanni M. Giammanco, Krisztián Bányai, S. De Grazia, Renáta Dóró, Hajnalka Papp, Eszter Mihalov-Kovács |
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| Přispěvatelé: | Papp, H., Mihalov-Kovács, E., Dóró, R., Marton, S., Farkas, S., Giammanco, G., De Grazia, S., Martella, V., Bányai, K. |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Rotavirus
Settore MED/07 - Microbiologia E Microbiologia Clinica Genotype constellation Molecular Sequence Data Genome Viral Biology medicine.disease_cause Genome Rotavirus Infections Viral Proteins Dogs Phylogenetic analysi Genetic Phylogenetics Zoonosi Sequence Homology Nucleic Acid Semiconductor sequencing Virology Genotype Genetics medicine Animals Humans Dog Diseases Molecular Biology Phylogeny Whole genome sequencing Hungary NSP1 Base Sequence Strain (biology) General Medicine Ion semiconductor sequencing Italy |
| Popis: | A canine Rotavirus A strain was identified in the fecal specimen of a young dog during 2012 in Hungary. The strain RVA/Dog-wt/HUN/135/2012/G3P[3] shared complete genotype constellation (G3-P[3]-I3-R3-C3-M3-A15-N2-T3-E3-H6) and high genome sequence similarity (nt, 98.8 %) with a historic human strain, RVA/Human-tc/ITA/PA260-97/1997/G3P[3]. This study provides evidence for the canine origin of the unusual NSP1 genotype, A15, and reinforces the hypothesis of direct interspecies transmission of canine rotaviruses to humans. |
| Databáze: | OpenAIRE |
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