Optic coherence tomography angiography follow-up in a case of Purtscher-like retinopathy due to atypical hemolytic uremic syndrome
| Autor: | Anna Serret Camps, Olga García García, Juan Francisco Santamaría Álvarez, Javier Aguayo Alvarez |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty genetic structures Computed Tomography Angiography Visual Acuity Antibodies Monoclonal Humanized Young Adult 03 medical and health sciences 0302 clinical medicine Retinal Diseases Purtscher like retinopathy Tomografia de coherència òptica Atypical hemolytic uremic syndrome medicine Humans Fluorescein Angiography Atypical Hemolytic Uremic Syndrome Optical coherence tomography medicine.diagnostic_test business.industry General Medicine Eculizumab medicine.disease Retinal diseases eye diseases Ophthalmology Malalties de la retina Complement Inactivating Agents Angiography 030221 ophthalmology & optometry Hemolytic anemia sense organs Radiology Tomography business Tomography Optical Coherence 030217 neurology & neurosurgery After treatment Anèmia hemolítica Follow-Up Studies medicine.drug Retinopathy Coherence (physics) |
| Zdroj: | Dipòsit Digital de la UB Universidad de Barcelona |
| ISSN: | 1724-6016 1120-6721 |
| Popis: | Purpose: To report a case of Purtscher-like retinopathy due to atypical hemolytic uremic syndrome and the changes seen in the optical coherence tomography angiography before and after treatment with eculizumab. Case description: A 22-year-old man with an unremarkable medical history presented with acute, bilateral blurred vision and headache of 1-week duration. Best corrected visual acuity of 20/50 and 20/40, respectively, in the patient’s right eye and left eye. Funduscopy revealed multiple cotton-wool spots associated with intrarretinal fluid. Swept source optical coherence tomography revealed multifocal retinal detachments with increased choroidal thickness. Optical coherence tomography angiography showed areas of ischemia in both capillary plexus. Due to concurrent symptoms and laboratory analysis, he was diagnosed with atypical hemolytic uremic syndrome and secondary Purtscher-like retinopathy; therefore, treatment with eculizumab was initiated. After 2 months revascularization of the previous ischemic areas was seen in the optical coherence tomography angiography that were correlated with best corrected visual acuity improvement. Conclusion: Our findings suggest that evaluation of the macular capillary plexus revascularization by optical coherence tomography angiography during the disease could help to predict an improvement of best corrected visual acuity in these patients and the measurement of choroidal thickness could give us information about the resolution of the pathologic process. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|