Acute and chronic stress effects on performance in a forced-swim task
| Autor: | Hymie Anisman, Christopher R. Prince |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Physiology Learned helplessness Motor Activity behavioral disciplines and activities Coping methods Mice Norepinephrine Animal model Helplessness Learned Escape Reaction Stress Physiological medicine Animals Humans Chronic stress Forced swim Swimming Electroshock Motivation Stressor Social Isolation Shock (circulatory) medicine.symptom Psychology psychological phenomena and processes Clinical psychology |
| Zdroj: | Behavioral and neural biology. 42(2) |
| ISSN: | 0163-1047 |
| Popis: | The effects of uncontrollable stressors on performance in a subsequent forced-swim paradigm were assessed in mice. Uncontrollable shock initially induced behavioral invigoration; however, within 24 h of stressor application, swimming behavior was depressed relative to nonstressed mice. The controllability of the stressor did not influence the initial invigoration, being present among escapably shocked mice as well as among mice that received (yoked) inescapable shock. In contrast, the depression of responding evident 24 h after stressor application was related to the availability of behavioral coping methods. Finally, following repeated exposure to footshock there was no indication of adaptation to the behavioral changes ordinarily induced by acute shock stress. The data were related to the effects of uncontrollable stressors on escape performance, and with respect to the use of this preparation as an animal model of human depression. |
| Databáze: | OpenAIRE |
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