Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs
| Autor: | Zeynep Pekcan, Miyase Çinar, Barış Kürüm, Birkan Karsli, Ali Kumandaş |
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| Rok vydání: | 2020 |
| Předmět: |
Bupivacaine
General Veterinary business.industry Butorphanol Analgesic Pain scale 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry Veterinary Isoflurane Anesthesia Analgesia dog epidural opioid pain assessment Morphine Veteriner Hekimlik Medicine Animal Science and Zoology Epidural administration business Propofol medicine.drug |
| Zdroj: | Volume: 68, Issue: 1 27-32 Ankara Üniversitesi Veteriner Fakültesi Dergisi |
| ISSN: | 1300-0861 1308-2817 |
| Popis: | The aim of this study was to compare the postoperative analgesic effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine in hind limb and pelvic orthopedic operations in dogs. Three groups each containing 10 dogs were formed. Through the lumbosacral space, group B was administered bupivacaine, 1 mg kg-1; group BB was administered bupivacaine, 1 mg kg-1 and butorphanol, 0.25 mg kg-1; and group BM was administered bupivacaine, 1 mg kg-1 and morphine, 0.1 mg kg-1. Anaesthesia was induced with diazepam (0.2 mg kg-1) and propofol (5 mg kg-1) and maintenance with isoflurane in oxygen. Pain assessment was performed with the University of Melbourne Pain Scale (UMPS) by a blinded observer. Plasma cortisol levels were measured preoperatively and postoperatively. Postoperative pain scores were significantly lower at 2 hours in the group BM, and at 8 and 12 hours in the groups BB and BM compared to the group B (P=0.007). Group BM had a lower plasma cortisol level than the group B at 2 hours (P=0.002). Bupivacaine-butorphanol and bupivacaine-morphine use were shown to provide longer analgesia in the postoperative period; and the epidural administration of bupivacaine-butorphanol and bupivacaine-morphine was considered to be potentially useful in clinical practice. |
| Databáze: | OpenAIRE |
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