Norovirus epidemiology in South African children5 years hospitalised for diarrhoeal illness between 2009 and 2013
| Autor: | Cheryl Cohen, Maureen B. Taylor, Janet Mans, Rembuluwani Netshikweta, Karen H. Keddy, Bhavani Poonsamy, Jocelyn Moyes, Nicola Page, Kathleen Kahn, Sandrama Nadan, Sibongile Walaza, Shabir A. Madhi, Michelle J. Groome |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Diarrhea Pediatrics medicine.medical_specialty Epidemiology 030106 microbiology Disease Biology medicine.disease_cause Serology 03 medical and health sciences South Africa 0302 clinical medicine stomatognathic system medicine Humans 030212 general & internal medicine Prospective Studies Caliciviridae Infections Public health Norovirus Infant Newborn Infant Odds ratio Virology Original Papers Confidence interval Hospitalization Infectious Diseases Child Preschool Vomiting medicine.symptom |
| Zdroj: | Epidemiol Infect |
| ISSN: | 1469-4409 |
| Popis: | SUMMARYPublic health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, clinical characteristics and environmental features associated with NoV detection in hospitalized children P = 0·011) with none-to-mild dehydration (adjusted OR 0·5; 95% CI 0·3–0·7) compared with NoV-negative children. Amongst children testing NoV positive, HIV-infected children were more likely to have prolonged hospitalization and increased mortality compared with HIV-uninfected children. Continued surveillance will be important to consider the epidemic trends and estimate the burden and risk of NoV infection in SA. |
| Databáze: | OpenAIRE |
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