Modeling photon transport in transabdominal fetal oximetry
| Autor: | Gargi Vishnoi, Regine Choe, Steven L. Jacques, Britton Chance, Nirmala Ramanujam |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Photon
Biomedical Engineering Models Biological Fetal brain Biomaterials Optics Light source Fetus Pregnancy Abdomen medicine Fetal distress Humans Scattering Radiation Abdominal surface Photons Spectroscopy Near-Infrared business.industry Brain medicine.disease Fetal Blood Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Oxygen medicine.anatomical_structure Cerebrovascular Circulation Feasibility Studies Fluence rate Female Nuclear medicine business Blood Gas Monitoring Transcutaneous |
| Zdroj: | Journal of biomedical optics. 5(3) |
| ISSN: | 1083-3668 |
| Popis: | The possibility of optical oximetry of the blood in the fetal brain measured across the maternal abdomen just prior to birth is under investigation. Such measurements could detect fetal distress prior to birth and aid in the clinical decision regarding Cesarean section. This paper uses a perturbation method to model photon transport through an 8-cm-diam fetal brain located at a constant 2.5 cm below a curved maternal abdominal surface with an air/tissue boundary. In the simulation, a near-infrared light source delivers light to the abdomen and a detector is positioned up to 10 cm from the source along the arc of the abdominal surface. The light transport [W/cm2 fluence rate per W incident power] collected at the 10 cm position is Tm=2.2×10−6 cm−2 if the fetal brain has the same optical properties as the mother and Tf=1.0×10−6 cm−2 for an optically perturbing fetal brain with typical brain optical properties. The perturbation P=(Tf−Tm)/Tm is −53% due to the fetal brain. The model illustrates the challenge and feasibility of transabdominal oximetry of the fetal brain. © 2000 Society of Photo-Optical Instrumentation Engineers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|