Survival and outcomes after laparoscopic versus open curative resection for colon cancer
| Autor: | Salah Addin Falah, Marwah Sami M Hussain, Ahmad M. Zubaidi, Riyadh Hakami, Neamat Alturki, Maha Abdullah, Nadia Abd Aljomah, Eman D. Almotairi, Luai H. Ashari, Samar Al Homoud, Nahla Arab, Saeed Albalawi, Faroq Abdulfattah, Saad Al-Qahtani, Omar Al-Obaid, Abdullah Mohammed Abduldaem, Ali Alsaffar, Turki Alshammari, Fatima Ahmed Badahdah, Thamer Bin Traiki, Khayal Al-Khayal, Nasser Al-Sanea, Alaa Abduljabbar, Reem A. Alharbi, Naif Ali Albati |
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| Rok vydání: | 2019 |
| Předmět: |
Oncology
Curative resection Male medicine.medical_specialty Colorectal cancer MEDLINE Saudi Arabia lcsh:Medicine 030209 endocrinology & metabolism Disease-Free Survival Resection Cohort Studies 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Survival rate Neoplasm Staging Retrospective Studies business.industry lcsh:R Retrospective cohort study General Medicine Length of Stay Middle Aged medicine.disease Survival Rate Colonic cancer Treatment Outcome Colonic Neoplasms Female Laparoscopy Original Article business Cohort study Follow-Up Studies |
| Zdroj: | Annals of Saudi Medicine Annals of Saudi Medicine, Vol 39, Iss 3, Pp 137-142 (2019) |
| ISSN: | 0975-4466 |
| Popis: | BACKGROUND: Many studies have shown that open and laparoscopicsurgery for resection of colonic cancers produce similar short- and long-term results, but no data have been reported from Saudi Arabia. OBJECTIVE: Compare 3-year disease-free and overall survival after laparoscopic versus open curative resection for potentially curable colon cancer. DESIGN: Multicenter retrospective cohort study. SETTING: Tertiary academic hospital. PATIENTS AND METHODS: We analyzed data of patients who underwent curative resection for potentially curable colon cancer using the laparoscopic or open approach at three tertiary care centers during the period 2000-2015. MAIN OUTCOME MEASURES: Overall and disease-free 3-year survival were the primary endpoints. Secondary endpoints included conversion rate, duration of surgery, length of hospital stay, rate of wound infection, resumption of bowel function, number of lymph nodes retrieved, adequacy of resection and rate of recurrence. Risk factors for recurrence, including complete mesocolic excision, were assessed. SAMPLE SIZE: 721. RESULTS: Patient and tumor characteristics were similar in the two groups except for ASA class ( P P P P P =.0714). CONCLUSION: Overall and disease-free survival after the laparoscopic approach for curative resection of colon cancer is comparable to the open approach. LIMITATIONS: Retrospective design and the possibility of selection bias. CONFLICT OF INTEREST: None. |
| Databáze: | OpenAIRE |
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