The Glasgow Prognostic Score and fibrinogen to albumin ratio as prognostic factors in hospitalized patients with COVID-19
| Autor: | Önsel Öner, Mutlu Kuluöztürk, Teyfik Turgut, Figen Deveci |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Thorax medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Hospitalized patients GPS Fibrinogen Logistic regression Prognostic score law.invention 03 medical and health sciences need for intensive care unit 0302 clinical medicine law Albumins Internal medicine medicine Humans Immunology and Allergy 030212 general & internal medicine Original Research Retrospective Studies SARS-CoV-2 business.industry Public Health Environmental and Occupational Health Albumin COVID-19 FAR Prognosis mortality Intensive care unit 030228 respiratory system business Research Article medicine.drug |
| Zdroj: | Expert Review of Respiratory Medicine article-version (VoR) Version of Record |
| ISSN: | 1747-6356 1747-6348 |
| Popis: | Aim: This study aims to determine the prognostic value of the Glasgow Prognostic Score (GPS) and fibrinogen to albumin ratio (FAR) in patients with COVID-19. Methods: Electronic database records of 400 patients with COVID-19 were retrospectively analyzed and the initial levels of CRP, albumin, fibrinogen values were recorded. The ground-glass opacities (GGO) and consolidations were evaluated on thorax CT. Hospital mortality and the need for intensive care unit (ICU) transfer were determined as adverse outcomes. Results: It was determined that 345 patients (86.25%) were discharged while 31 patients (7.75%) were transferred to ICU in addition to 24 patients who died (6%). The rates of deaths and transfers to ICU were significantly increased in GPS 2 group compared to both GPS 0 and 1 groups. Additionally, increased FAR was observed in patients who died and transferred to ICU compared to the discharged patients. The FAR was significantly increased in patients with diffuse GGO. Logistic regression analysis indicated that FAR ≥144.59 and the presence of GPS 2 were independent predictors of the adverse outcomes in COVID-19 patients. Conclusion: Our results demonstrated that the GPS and FAR could possess a predictive value for adverse outcomes in patients with COVID-19. |
| Databáze: | OpenAIRE |
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