Mixed Cryoglobulinemia in Greece: Primary disorders in 10 cases
| Autor: | H. M. Moutsopoulos, V. Galanopoulou, G. D. Linardaki, Kyriaki A. Boki, G. Vaiopoulos, A. G. Tzioufas |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Systemic disease Hepatitis C virus Immunology medicine.disease_cause Dizziness Cryoglobulins Rheumatology Immunopathology Weight Loss medicine Humans Immunology and Allergy Purpura Aged Autoimmune disease Hepatitis B virus Greece business.industry Raynaud Disease General Medicine Middle Aged medicine.disease Cryoglobulinemia Female Viral disease Viral hepatitis business |
| Zdroj: | Scandinavian Journal of Rheumatology. 26:280-286 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.3109/03009749709105317 |
| Popis: | Mixed cryoglobulinemia (MC) is a systemic disorder whose pathogenesis is based on the presence of serum cryoglobulins. The purpose of this study was to evaluate on a prospective basis patients presenting with MC with regard to the clinical manifestations and the underlying disorders. We present ten patients with MC, who were diagnosed and followed up during a one year period in the Division of autoimmune rheumatic diseases (Clinical Department of Pathophysiology). MC was associated with hepatitis C virus (HCV) infection in two cases, with hepatitis B virus (HBV) infection in six, one patient had both HCV and evidence of HBV infection, while the remaining three patients fulfilled European classification criteria for diagnosis of Sjögren's syndrome (SS). In all ten cases, the presence of an underlying factor was identified, being either viral or autoimmune. It is concluded therefore that all patients presenting with MC should be completely evaluated for a hepatitis virus infection or an autoimmune or lymphoproliferative disorder. Furthermore, since the initiation of the process of MC is triggered by many factors, research should be directed towards the identification of the underlying common denominator. |
| Databáze: | OpenAIRE |
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