Green algal hydrocarbon metabolism is an exceptional source of sustainable chemicals
| Autor: | Julian Wichmann, Olaf Kruse, Kyle J. Lauersen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Microorganism Biomedical Engineering Bioengineering Chlorophyta Photosynthesis 01 natural sciences 660.6 03 medical and health sciences chemistry.chemical_compound Bioenergy 010608 biotechnology Microalgae 030304 developmental biology chemistry.chemical_classification 0303 health sciences biology Metabolism Carbon Dioxide biology.organism_classification Hydrocarbons Hydrocarbon chemistry Environmental chemistry Carbon dioxide Environmental science Green algae Biotechnology |
| Zdroj: | Current Opinion in Biotechnology. 61:28-37 |
| ISSN: | 0958-1669 |
| DOI: | 10.1016/j.copbio.2019.09.019 |
| Popis: | Microalgae are rapidly growing, low-input requiring, sun light-utilizing microorganisms capable of converting carbon dioxide into various natural products, a major portion of which are hydrocarbons. Their cellular compartmentalization and photosynthetic apparatus depend on robust turnover of two hydrocarbon classes, isoprenoids and acyl-lipids. This review summarizes the current understanding of algal hydrocarbon metabolism, including carbon partitioning capacities, the localization and size of precursor pools, environmental effects on flux distribution, and limiting factors towards efficient (heterologous) hydrocarbon production. Questions and challenges regarding our knowledge of algal hydrocarbon metabolism as well as guidelines for systematic engineering are presented. Recent engineering achievements indicate fundamental plasticity in the (heterologous) hydrocarbon metabolism of green algae while highlighting their potential as renewable sources of these products. Copyright © 2019 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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