Percutaneous alcohol injection of portal thrombosis in hepatocellular carcinoma: a new possible treatment

Autor: Grigioni W, A. Mazziotti, Gabriele Sangalli, Tito Livraghi, C Vettori
Rok vydání: 1990
Předmět:
Zdroj: Tumori. 76(4)
ISSN: 0300-8916
Popis: Hepatocellular carcinoma (HCC) with portal thrombosis is usually regarded as a contraindication for surgery and for percutaneous alcohol injection (PAI). For palliative purposes we used PAI in 4 patients with infiltrative HCC and segmental portal thrombosis. Ethanol, injected directly into the thrombus, diffused mostly along it. No complications emerged after 20 injections. In the first patient, who later a liver transplant, the thrombus was completely necrotic. In the other patients, biopsies yielded only necrotic material: in two cases, progression of the thrombus was stopped at 4 and 12 months of follow-up, and in one case the thrombus shrank and remained as such 13 months later. This preliminary experience might broaden the scope of treatment for HCC.
Databáze: OpenAIRE