Welding and the risk of head and neck cancer: the ICARE study
| Autor: | Joelle Fevotte, Loredana Radoï, Julien Dugas, Aviane Auguste, Anne-Valérie Guizard, Christine Barul, Danièle Luce, Gwenn Menvielle, Mireille Matrat, Isabelle Stücker |
|---|---|
| Přispěvatelé: | Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Fonds d'indemnisation des victimes de l'amiante (FIVA), Registre des cancers du Calvados, Fondation pour la Recherche Médicale, Association pour la Recherche sur le Cancer, Institut de Veille Sanitaire, Fondation de France, Agence Nationale de la Recherche, Ministry of Labour, Ministry of Health, French Agency for Food, Environmental and Occupational Health and Safety, Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Larynx Epidemiology Occupational safety and health head and neck 0302 clinical medicine Risk Factors Welding ComputingMilieux_MISCELLANEOUS education.field_of_study Confounding Middle Aged 030210 environmental & occupational health 3. Good health Occupational Diseases Oropharyngeal Neoplasms medicine.anatomical_structure Head and Neck Neoplasms 030220 oncology & carcinogenesis France Adult medicine.medical_specialty tumor Adolescent case-control study Population [SDV.CAN]Life Sciences [q-bio]/Cancer Young Adult 03 medical and health sciences Occupational Exposure Internal medicine medicine Humans Neoplasms Squamous Cell education Laryngeal Neoplasms Aged [SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/Health Hypopharyngeal Neoplasms business.industry Head and neck cancer Public Health Environmental and Occupational Health Case-control study Cancer Pharyngeal Neoplasms medicine.disease Logistic Models Case-Control Studies occupational health [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business |
| Zdroj: | Occupational and Environmental Medicine Occupational and Environmental Medicine, BMJ Publishing Group, 2020, 77 (5), pp.293-300. ⟨10.1136/oemed-2019-106080⟩ Occupational and Environmental Medicine, 2020, 77 (5), pp.293-300. ⟨10.1136/oemed-2019-106080⟩ |
| ISSN: | 1351-0711 |
| DOI: | 10.1136/oemed-2019-106080⟩ |
| Popis: | ObjectiveTo investigate the association between occupational exposure to welding and the risk of head and neck cancer in a large French population-based case-control study, the Investigation of occupational and environmental CAuses of REspiratory cancers study.MethodsAnalyses were restricted to men (2703 controls and 1588 cases of squamous-cell carcinoma of the oral cavity, oropharynx, hypopharynx and larynx). Welding activity and potential confounders were assessed by detailed questionnaires. ORs and CIs (95% CI) were estimated by unconditional logistic regression, adjusted for age, area of residence, tobacco smoking, alcohol consumption and occupational exposure to asbestos.ResultsWelding was associated with an increased risk of head and neck cancer overall (OR=1.31, 95% CI 1.03 to 1.67). The association was strongest for laryngeal cancer (OR=1.66, 95% CI 1.15 to 2.38) and the risk increased with the cumulative duration (p-trend ConclusionOur findings suggest that welding and several welding-related tasks increase the risk of laryngeal cancer and to a lesser extent oral cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|