Study of the acute and repeated dose 28-day oral toxicity in mice treated with PT-31, a molecule with a potential antipsychotic profile

Autor:	Thalia Emmanoella Sebulsqui Saraiva, Gabriela Zimmermann Prado Rodrigues, Juliana Machado Kayser, Eliane Dallegrave, Nathália Pulz Maus, Andriele Veiverberg, Gabriel da Costa Berna, Andriéli Carolina Schuster, Maria Gabriela de Freitas, Marina Galdino da Rocha Pitta, Ivan da Rocha Pitta, Günther Gehlen, Andresa Heemann Betti
Rok vydání:	2022
Předmět:	Mice Liver Health Toxicology and Mutagenesis Toxicity Tests Acute Animals Humans Female Toxicology Kidney Lipids Antipsychotic Agents
Zdroj:	Toxicology mechanisms and methods. 32(9)
ISSN:	1537-6524
Popis:	Schizophrenia is a psychiatric disorder that affects 1% of the world population and is treated with antipsychotics, which may induce important biochemical and hematological alterations. Since it is necessary to verify the safety of new molecules with antipsychotic potential, the present study aimed to evaluate the oral toxicity of PT-31, a putative α
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc03ceb3003cd8ddd10fdd8e6fab3e0 https://pubmed.ncbi.nlm.nih.gov/35410575 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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