COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine
| Autor: | Marco Ballestri, Francesca Damiano, Lorenzo Tei, Alessio Amurri, Riccardo Magistroni, Marco Leonelli, Gianni Cappelli, Francesca Facchini, Francesco Fontana, Gaetano Alfano, Giacomo Mori |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
infectious disease medicine.medical_treatment Case Report kidney transplantation/nephrology Case Reports immunosuppressant – fusion proteins and monoclonal antibodies 030230 surgery clinical research/practice immunosuppressant - fusion proteins and monoclonal antibodies infection and infectious agents - viral 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Tocilizumab Internal medicine Pandemic medicine Immunology and Allergy Pharmacology (medical) Kidney transplantation Mechanical ventilation Transplantation business.industry infection and infectious agents – viral Hydroxychloroquine Immunosuppression medicine.disease Comorbidity chemistry Infectious disease (medical specialty) business medicine.drug |
| Zdroj: | American Journal of Transplantation |
| Popis: | Coronavirus disease 2019 (COVID‐19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61‐year‐old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID‐19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic, transplant clinicians should be readily informed about new cases of COVID‐19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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