Do routine antibiotics after loop diathermy excision reduce morbidity?
| Autor: | J. Foden-Shroff, J. Millinship, Adrian Warwick, H. Tucker, Charles W.E. Redman, Peter W. Jones, E. Thomas |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Ofloxacin medicine.medical_specialty Randomization medicine.drug_class medicine.medical_treatment Vaginal Diseases Antibiotics Uterine Cervical Neoplasms Placebo Double-Blind Method Diathermy medicine Humans Prospective Studies Antibiotic prophylaxis Colposcopy Chemotherapy medicine.diagnostic_test business.industry Obstetrics and Gynecology Antibiotic Prophylaxis Middle Aged Uterine Cervical Dysplasia Anti-Bacterial Agents Surgery Endoscopy Female Uterine Hemorrhage business |
| Zdroj: | BJOG: An International Journal of Obstetrics and Gynaecology. 105:1022-1025 |
| ISSN: | 1471-0528 1470-0328 |
| DOI: | 10.1111/j.1471-0528.1998.tb10268.x |
| Popis: | Objective To evaluate whether routinely giving an antibiotic after loop diathermy excision of the cervical transformation zone reduced post-operative vaginal loss. Design Prospective, randomised, double-blind placebo controlled parallel study. Participants Five hundred women undergoing loop diathermy excision in a colposcopy clinic. Intervention Administration of either ofloxacin 400 mg (2 × 200 mg) once daily for 5 days or an identical placebo. Main outcome measure Vaginal loss, assessed using a pictorial chart. Results No significant difference in post-operative vaginal loss was found. Conclusion Routine antibiotic prophylaxis after loop diathermy excision is not justified. |
| Databáze: | OpenAIRE |
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