Chiral Recognition of α-Amino Acids by an Optically Active (2S,5S,8S,11S)-2,5,8,11-Tetraethyl Cyclen Cobalt(III) Complex
| Autor: | Sei Tsuboyama, Yasuyo Ogura, Mitsuhiko Shionoya, Shohei Tashiro, Kaoru Tsuboyama |
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| Rok vydání: | 2010 |
| Předmět: |
Models
Molecular chemistry.chemical_classification Steric effects Magnetic Resonance Spectroscopy Chemistry Stereochemistry Dimethyl sulfoxide Glycine chemistry.chemical_element Stereoisomerism Cobalt Crystal structure Optically active Crystallography X-Ray Amino acid Inorganic Chemistry chemistry.chemical_compound Cyclen Coordination Complexes Heterocyclic Compounds Leucine Ethyl group Physical and Theoretical Chemistry |
| Zdroj: | Inorganic Chemistry. 50:4-6 |
| ISSN: | 1520-510X 0020-1669 |
| Popis: | The optically active cobalt(III) complex with chiral cyclen, (2S,5S,8S,11S)-2,5,8,11-tetraethyl-1,4,7,10-tetraazacyclododecane, preferentially binds to D-phenylglycine (D-Phg) or D-t-leucine (D-t-Leu) rather than L-Phg or L-t-Leu, respectively, with 20% de in dimethyl sulfoxide at 293 K. Comparative studies on the crystal structures of cobalt(III) complexes with d-Phg and l-Phg revealed that the diastereoselectivity is due to the difference in the steric hindrance that should occur between the amino group of Phg and the ethyl group of cyclen. |
| Databáze: | OpenAIRE |
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