Relationship among angiotensin-converting enzyme polymorphism, cardiovascular risk, and osteoporotic fractures
| Autor: | Francisca Cuadrado-Medina, Laisa Socorro Briongos-Figuero, Monica Pineda-Alonso, Laura Abad-Manteca, José Luis Pérez-Castrillón, Gemma Vega-Tejedor |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
biology business.industry Osteoporosis 030209 endocrinology & metabolism Angiotensin-converting enzyme Disease 030204 cardiovascular system & hematology medicine.disease Gastroenterology Comorbidity Cardiovascular physiology Bone remodeling 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Genotype biology.protein Medicine Lumbar spine business Original Investigation |
| Zdroj: | European Journal of Rheumatology. 3:10-12 |
| ISSN: | 2148-4279 2147-9720 |
| Popis: | OBJECTIVE Angiotensin-converting enzyme (ACE) has been related to cardiovascular physiology and bone remodeling. Our aim was to assess the relationship among ACE polymorphisms, cardiovascular risk, and osteoporotic fractures. MATERIAL AND METHODS We prospectively enrolled 71 patients with hypertension from 2001 to 2014. Sociodemographic and medical data were collected. Comorbidity was evaluated with Charlson index. Densitometric studies on lumbar spine were performed. ACE polymorphism was analyzed by polymerase chain reaction. Data were analyzed using SPSS 15.0 (p value |
| Databáze: | OpenAIRE |
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