Expression of prostaglandin EP2 receptor mRNA in the rat spinal cord

Autor:	Takeshi Yamauchi, Toru Kawamura, Tomoyuki Maruyama, Norifirmi Nakamura, Toshiaki Akira, Mamoru Koyama
Rok vydání:	1997
Předmět:	Male endocrine system medicine.medical_specialty Prostaglandin E2 receptor In situ hybridization Polymerase Chain Reaction General Biochemistry Genetics and Molecular Biology Internal medicine medicine Animals Receptors Prostaglandin E RNA Messenger Rats Wistar General Pharmacology Toxicology and Pharmaceutics Prostaglandin E2 In Situ Hybridization urogenital system Chemistry General Medicine Blotting Northern Spinal cord Rats Cell biology Endocrinology Nociception medicine.anatomical_structure Spinal Cord nervous system Reflex Prostaglandin EP2 receptor lipids (amino acids peptides and proteins) Signal transduction Signal Transduction medicine.drug
Zdroj:	Life Sciences. 61:2111-2116
ISSN:	0024-3205
DOI:	10.1016/s0024-3205(97)00884-9
Popis:	RT-PCR and an in situ hybridization analyses demonstrated expression of prostaglandin EP2 receptor mRNA in the subfield of the dorsal horn of the rat spinal cord. The intensive signals from the cells labeled with digoxigenin-11-dUTP were scattered through this region and they corresponded to neurons. EP2 receptor-mediated signal transduction is expected to play roles in modulating some neuronal functions such as transmission of nociceptive reaction or motor reflex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda75e7b67343e69f6265b05d902e76a https://doi.org/10.1016/s0024-3205(97)00884-9 Zobrazit plný text záznamu Full Text from ScienceDirect