The analysis of linear and monomethylalkanes in exhaled breath samples by GC×GC-FID and GC–MS/MS
| Autor: | Viktória Ferenczy, Ladislav Soják, Anton Amann, Václav Matěj Bierhanzl, Jozef Višňovský, Róbert Kubinec, Ivan Ostrovský, Peter Podolec, Gabriela Addová, Radomír Čabala, Jaroslav Blaško, Renáta Górová, Alexandra Hengerics Szabó |
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| Rok vydání: | 2015 |
| Předmět: |
Detection limit
Analyte N alkanes Sorbent Chromatography Chemistry Clinical Biochemistry Analytical chemistry Reproducibility of Results Cell Biology General Medicine Biochemistry Gas Chromatography-Mass Spectrometry Analytical Chemistry Breath Tests Limit of Detection Tandem Mass Spectrometry Alkanes Humans Kovats retention index Gas chromatography–mass spectrometry |
| Zdroj: | Journal of Chromatography B. :62-69 |
| ISSN: | 1570-0232 |
| Popis: | A new arrangement of the INCAT (inside needle capillary adsorption trap) device with Carbopack X and Carboxen 1000 as sorbent materials was applied for sampling, preconcentration and injection of C6 C19 n-alkanes and their monomethyl analogs in exhaled breath samples. For the analysis both GC–MS/MS and GC × GC-FID techniques were used. Identification of the analytes was based on standards, measured retention indices and selective SRM transitions of the individual isomers. The GC–MS/MS detection limits were in the range from 2.1 pg for n-tetradecane to 86 pg for 5-methyloctadecane. The GC × GC-FID detection limits ranged from 19 pg for n-dodecane to 110 pg for 3-methyloctane. |
| Databáze: | OpenAIRE |
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