Effect of green tea extract on arterial stiffness, lipid profile and sRAGE in patients with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled trial

Autor: Esther N Sanchez-Rodriguez, Maricruz Barocio-Pantoja, Leonel García-Benavides, David Cardona-Müller, Walter A Trujillo-Rangel, Mariana Rodríguez-De la Cerda, Fernando Grover-Páez, Carlos G Ramos-Becerra, Jhonatan Trujillo-Quiros, Patricia Quezada-Fernández, Sara Pascoe-González, Ernesto Germán Cardona-Muñoz
Rok vydání: 2019
Předmět:
0301 basic medicine
Male
endocrine system diseases
Receptor for Advanced Glycation End Products
Placebo-controlled study
Green tea extract
Gastroenterology
Body Mass Index
0302 clinical medicine
Glycation
Medicine
medicine.diagnostic_test
S100 Proteins
Alanine Transaminase
Middle Aged
musculoskeletal system
Cholesterol
Creatinine
cardiovascular system
Body Composition
Female
circulatory and respiratory physiology
Adult
medicine.medical_specialty
030209 endocrinology & metabolism
Double blind
03 medical and health sciences
Vascular Stiffness
Double-Blind Method
Internal medicine
Diabetes mellitus
Humans
Aspartate Aminotransferases
Triglycerides
Glycated Hemoglobin
030109 nutrition & dietetics
Tea
business.industry
Plant Extracts
Cholesterol
HDL

Hemodynamics
nutritional and metabolic diseases
Type 2 Diabetes Mellitus
Polyphenols
Cholesterol
LDL

medicine.disease
Lipid Metabolism
Diabetes Mellitus
Type 2

Dietary Supplements
Arterial stiffness
business
Lipid profile
Food Science
Zdroj: International journal of food sciences and nutrition. 70(8)
ISSN: 1465-3478
Popis: Type 2 diabetes mellitus (T2DM) is associated with premature atherosclerosis and arterial stiffening due to the accumulation of advanced glycation end-products in vessel walls. Green tea polyphenols are considered cardio-protective substances. In this randomised double-blind placebo-controlled trial (NCT02627898), we evaluated the effect of Green tea extract on arterial stiffness parameters, lipids, body composition and sRAGE levels. Twenty normotensive patients with T2DM treated with the standard therapy and statins, mean age 53.2 ± 9.4 years and mean BMI 30.1 ± 4.5 kg/m
Databáze: OpenAIRE
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