Prognostic significance of regional lymph node metastasis according to station in ampullary carcinoma
| Autor: | Junji Yamamoto, Yoji Kishi, Keita Tashiro, Kazuo Hase, Naomi Kuroki, Takahiro Einama, Hideki Ueno, Yu Takahashi, Yosuke Inoue, Yoichi Miyata, Sho Ogata, Suefumi Aosasa, Toshimitsu Iwasaki |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Oncology
Ampulla of Vater medicine.medical_specialty Multivariate analysis 030230 surgery Metastasis 03 medical and health sciences 0302 clinical medicine Regional lymph node metastasis Internal medicine medicine Humans Lymph node Neoplasm Staging Retrospective Studies Ampullary carcinoma Hepatology business.industry Hazard ratio Prognosis medicine.disease Confidence interval Survival Rate medicine.anatomical_structure Lymphatic Metastasis 030220 oncology & carcinogenesis Lymph Node Excision Surgery Lymph Nodes Lymph Neoplasm Recurrence Local business |
| Zdroj: | Journal of Hepato-Biliary-Pancreatic Sciences. 27:712-720 |
| ISSN: | 1868-6982 1868-6974 |
| DOI: | 10.1002/jhbp.791 |
| Popis: | BACKGROUND The TNM (Tumor, Node, Metastasis) classification of the 8th Union for International Cancer Control and the 6th Japanese classification of biliary tract cancer were made on the premise that the prognostic effect of each regional lymph node station is similar. However, some studies have reported different effects of lymph node metastasis location on post-resection prognosis. This study aimed to investigate outcome following radical resection of ampullary carcinoma according to station of lymph node metastasis. METHODS Patients who underwent surgical resection for ampullary carcinoma between January 2007 and December 2017 at two separate Japanese institutions were included. Regional lymph nodes were subclassified as follows: Pancreatoduodenal lymph nodes (PD) and others (OT). RESULTS Of the 101 patients analyzed, 34 had regional lymph node metastasis. OT metastasis was found in eight patients. Significant differences were found in relapse-free survival (RFS) and overall survival (OS) between the three study groups (no nodal metastasis, only PD metastasis and OT metastasis; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text