Antimicrobial effect of platelet-rich plasma and platelet-rich fibrin
| Autor: | Swapna A Mahale, Pallavi Badade, Alisha Panjwani, Prutha Vaidya, Ayushya Warang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male blood platelets platelet-rich fibrin Context (language use) Aggregatibacter actinomycetemcomitans Fibrin Microbiology 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents Humans Medicine Platelet 030212 general & internal medicine General Dentistry Porphyromonas gingivalis biology business.industry platelet-rich plasma 030206 dentistry General Medicine Middle Aged biology.organism_classification Platelet-rich fibrin lcsh:RK1-715 Antimicrobial effect lcsh:Dentistry Platelet-rich plasma Immunology biology.protein business Wound healing |
| Zdroj: | Indian Journal of Dental Research, Vol 27, Iss 3, Pp 300-304 (2016) |
| ISSN: | 0970-9290 |
| DOI: | 10.4103/0970-9290.186231 |
| Popis: | Context: Platelet concentrates have been extensively used in a variety of medical fields to promote soft- and hard-tissue regeneration. The significance behind their use lies in the abundance of growth factors (GFs) in platelets α-granules that promote wound healing. Other than releasing a pool of GFs upon activation, platelets also have many features that indicate their role in the anti-infective host defense. Aim: The aim of this study is to evaluate the antimicrobial activities of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) against periodontal disease-associated bacteria. Subjects and Methods: Blood samples were obtained from ten adult male patients. PRP and PRF were procured using centrifugation. The antimicrobial activity of PRP and PRF was evaluated by microbial culturing using bacterial strains of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Results: P. gingivalis and A. actinomycetemcomitans were inhibited by PRP but not by PRF. Conclusions: PRP is a potentially useful substance in the fight against periodontal pathogens. This might represent a valuable property in adjunct to the enhancement of tissue regeneration. |
| Databáze: | OpenAIRE |
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