Bisphenol A: Perinatal exposure and body weight
| Autor: | Ana M. Soto, Beverly S. Rubin |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Thyroid Hormones endocrine system medicine.medical_specialty Bisphenol A Peroxisome Proliferator-Activated Receptors Population Diethylstilbestrol Urine Endocrine Disruptors Biochemistry Article chemistry.chemical_compound Endocrinology Phenols Pregnancy Internal medicine Adipocytes medicine Animals Humans Adiponectin secretion Estrogens Non-Steroidal Benzhydryl compounds Benzhydryl Compounds education Molecular Biology education.field_of_study Estradiol Molecular Structure Perinatal Exposure urogenital system Body Weight Glucose Receptors Estrogen chemistry Maternal Exposure Prenatal Exposure Delayed Effects Toxicity Female hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Molecular and Cellular Endocrinology. 304:55-62 |
| ISSN: | 0303-7207 |
| DOI: | 10.1016/j.mce.2009.02.023 |
| Popis: | Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from products in contact with food and drink, and is therefore thought to be routinely ingested. In a recent cross sectional study, BPA was detected in urine samples from 92.6% of the US population examined. The potential for BPA to influence body weight is suggested by in vitro studies demonstrating effects of BPA on adipocyte differentiation, lipid accumulation, glucose transport and adiponectin secretion. Data from in vivo studies have revealed dose-dependent and sex dependent effects on body weight in rodents exposed perinatally to BPA. The mechanisms through which perinatal BPA exposure acts to exert persistent effects on body weight and adiposity remain to be determined. Possible targets of BPA action are discussed. |
| Databáze: | OpenAIRE |
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