Alcohol consumption in patients with colorectal adenomatous polyps
| Autor: | Peter N. Lee, Judith I. Wyatt, J. Kelleher, G F Cope, I F Pinder, Richard V. Heatley |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Adenomatous polyps medicine.medical_specialty Alcohol Drinking Colon Colorectal cancer Rectum Gastroenterology Risk Factors Internal medicine Epidemiology medicine Carcinoma Humans In patient Risk factor Aged Aged 80 and over business.industry Smoking Intestinal Polyps Middle Aged medicine.disease digestive system diseases medicine.anatomical_structure Female Colorectal Neoplasms business Alcohol consumption Research Article |
| Zdroj: | Gut. 32:70-72 |
| ISSN: | 0017-5749 |
| DOI: | 10.1136/gut.32.1.70 |
| Popis: | The risk of developing colorectal adenomatous polyps is probably increased by a variety of dietary and environmental factors. We found an association with current alcohol and cigarette consumption. The risk of polyps was increased three times in drinkers who did not smoke and two times in smokers who did not drink, with those who both drank and smoked having 12 times the risk of total abstainers. Since colonic adenomatous polyps are generally regarded as premalignant lesions, these results lend support to the view that alcohol consumption may be an important factor in the pathogenesis of colorectal neoplasia, thus reinforcing the proposed polyp/carcinoma sequence in colorectal carcinogenesis. The role of smoking, however, is less clear particularly since the lack of association of colorectal carcinoma and smoking has been reported in many other studies. |
| Databáze: | OpenAIRE |
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