Evaluation of nasal function after endoscopic endonasal surgery for pituitary adenoma: a computational fluid dynamics study

Autor: Miao Lou, Luyao Zhang, Simin Wang, Ruiping Ma, Minjie Gong, Zhenzhen Hu, Jingbin Zhang, Yidan Shang, Zhenbo Tong, Guoxi Zheng, Ya Zhang
Rok vydání: 2021
Předmět:
Zdroj: Computer Methods in Biomechanics and Biomedical Engineering. 25:1449-1458
ISSN: 1476-8259
1025-5842
DOI: 10.1080/10255842.2021.2016721
Popis: To analyze the effect of different endoscopic endonasal approaches (EEAs) on nasal airflow and heating and humidification in patients with pituitary adenoma (PA) by computational fluid dynamics (CFD).A three-dimensional pre-surgical model (Pre) of the nasal cavity and 6 that were post-EEA surgery were created from computed tomography scans as follows: small posterior septectomy (0.5 cm, sPS), middle posterior septectomy (1.5 cm, mPS), large posterior septectomy (2.5 cm, lPS), and sPS with middle turbinate resection (sPS-MTR), mPS-MTR, and lPS-MTR. Simulations were performed by CFD to compare the changes in different models.The temperature in the nasal vestibule rose more rapidly than in other parts of the nasal cavities in all models. There were no apparent differences in temperature and humidity among the models in sections anterior to the middle turbinate head (C6 section). MTR significantly influenced airflow distribution between the bilateral nasal cavities and the different parts of the nasal cavity, while changes in temperature and humidity in each section were mainly affected by MTR. The temperature and humidity of the choana and nasopharynx of each postoperative model were significantly different from those of the preoperative model and the change in values significantly correlated with the surface-to-volume ratio (SVR) of the airway.Changes due to the different nasal structures caused different effects on nasal function following the use of EEA surgery for the treatment of PA. CFD provided a new approach to assess nasal function, promising to provide patients with individualized preoperative functional assessment and surgical planning.
Databáze: OpenAIRE
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