Crimean-Congo Hemorrhagic Fever in Turkey
Autor: | Mustafa Yilmaz, Ercument Ovali, Iftihar Koksal, Mehmet Sönmez, Martin J. Vincent, Pierre E. Rollin, James A. Comer, Bobbie R. Erickson, Necmi Eren, Rahmet Caylan, Stuart T. Nichol, Volkan Korten, S Sami Karti, Zekaver Odabasi, Elif Akdogan, Thomas G. Ksiazek |
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Rok vydání: | 2004 |
Předmět: |
Adult
Male Microbiology (medical) Crimean–Congo hemorrhagic fever Turkey Epidemiology lcsh:Medicine Antibodies Viral Virus lcsh:Infectious and parasitic diseases Phagocytosis medicine Humans lcsh:RC109-216 CCHF VIRUS Phylogeny biology business.industry Research hemorrhagic fever virus lcsh:R infection-associated Sequence Analysis DNA Middle Aged Serum samples medicine.disease Virology Infectious Diseases Immunoglobulin M Immunoglobulin G Hemorrhagic Fever Virus Crimean-Congo biology.protein Female Hemorrhagic Fever Crimean Hemophagocytosis Antibody business Crimean-Congo hemophagocytic syndrome Crimean Congo hemorrhagic fever virus |
Zdroj: | Emerging Infectious Diseases Emerging Infectious Diseases, Vol 10, Iss 8, Pp 1379-1384 (2004) |
ISSN: | 1080-6059 1080-6040 |
Popis: | Nineteen cases of suspected Crimean-Congo hemorrhagic fever reported from Turkey. In 2002 and 2003, a total of 19 persons in Turkey had suspected cases of Crimean-Congo hemorrhagic fever (CCHF) or a similar viral infection. Six serum samples were tested; all six were found positive for immunoglobulin M antibodies against CCHF virus. Two of the samples yielded CCHF virus isolates. Genetic analysis of the virus isolates showed them to be closely related to isolates from former Yugoslavia and southwestern Russia. These cases are the first of CCHF reported from Turkey. Eighteen patients handled livestock, and one was a nurse with probable nosocomial infection. The case-fatality rate was 20% among confirmed CCHF case-patients (1 of 5 patients), and the overall case-fatality rate was 11% (2 of 19 patients). In addition to previously reported symptoms and signs, we report hemophagocytosis in 50% of our patients, which is the first report of this clinical phenomenon associated with CCHF. |
Databáze: | OpenAIRE |
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