Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil
Autor: | Ludmilla Santos Silva de Mesquita, Patrícia de Maria Silva Figueiredo, Jayakumar Bose, Sonia Malik, Rambod Abiri, Lívio Martins Costa-Júnior, Carolina R. Silva, José Wilson Carvalho de Mesquita, Emmeline De Sá Rocha |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
lcsh:Medicine
lcsh:RS1-441 Pharmaceutical Science Sesquiterpene 01 natural sciences Article law.invention lcsh:Pharmacy and materia medica GCMS-chromatography 03 medical and health sciences chemistry.chemical_compound law Drug Discovery (compositae) Candida albicans Essential oil 030304 developmental biology Artemisia vulgaris 0303 health sciences germacrene-D caryophyllene biology Humulene Traditional medicine anthelmintic Caryophyllene lcsh:R humulene biology.organism_classification Antimicrobial 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Molecular Medicine antimicrobial Haemonchus contortus |
Zdroj: | Pharmaceuticals Volume 12 Issue 2 Pharmaceuticals, Vol 12, Iss 2, p 49 (2019) |
ISSN: | 1424-8247 |
DOI: | 10.3390/ph12020049 |
Popis: | Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic. The constituents of essential oils isolated by hydro-distillation were examined by GC-MS and a total of 18 components were identified. The essential oil was dominated by oxygenated sesquiterpenes (44.4%), sesquiterpene hydrocarbons (33.3%), and oxygenated monoterpenes (16.6%). Caryophyllene (37.45%), germacrene D (16.17%), and humulene (13.66%) were the major components. The essential oils from A. vulgaris showed bactericidal and fungicidal properties against Staphylococcus aureus and Candida albicans, respectively. Anthelmintic activity against Haemonchus contortus was absent in this essential oil. Altogether above results indicate that essential oils from A. vulgaris can be used for various medicinal purposes. |
Databáze: | OpenAIRE |
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