Nutritional status and risk of contrast-associated acute kidney injury in elderly patients undergoing percutaneous coronary intervention
| Autor: | Haoming He, Weiping Zheng, Chen He, Feng Jiang, Kaiyang Lin, Hanchuan Chen, Zhebin You, Xiaoqi Wei, Jie Yang |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Physiology Anemia medicine.medical_treatment Contrast Media Nutritional Status Controlling Nutritional Status (CONUT) score Lower risk Percutaneous coronary intervention Elderly Risk Factors Physiology (medical) Internal medicine Medicine Humans Aged Retrospective Studies Aged 80 and over Univariate analysis business.industry Incidence Malnutrition Acute kidney injury Patient Acuity Odds ratio Acute Kidney Injury medicine.disease Contrast-associated acute kidney injury Nephrology Conventional PCI Original Article Female business |
| Zdroj: | Clinical and Experimental Nephrology |
| ISSN: | 1437-7799 1342-1751 |
| Popis: | Background This study aimed to investigate the connection between malnutrition evaluated by the Controlling Nutritional Status (CONUT) score and the risk of contrast-associated acute kidney injury (CA-AKI) in elderly patients who underwent percutaneous coronary intervention (PCI). Methods A total of 1308 patients aged over 75 years undergoing PCI was included. Based on the CONUT score, patients were assigned to normal (0–1), mild malnutrition (2–4), moderate-severe malnutrition group (≥ 5). The primary outcome was CA-AKI (an absolute increase in ≥ 0.3 mg/dL or ≥ 50% relative serum creatinine increase 48 h after contrast medium exposure). Results Overall, the incidence of CA-AKI in normal, mild, moderate-severe malnutrition group was 10.8%, 11.0%, and 27.2%, respectively (p p = 0.02; OR = 0.46, 95%CI: 0.26–0.82, p = 0.009, respectively). Furthermore, the relationship were consistent across the subgroups classified by risk factors for CA-AKI except anemia. The risk of CA-AKI related with CONUT score was stronger in patients with anemia. (overall interaction p by CONUT score = 0.012). Conclusion Moderate-severe malnutrition is associated with higher risk of CA-AKI in elderly patients undergoing PCI. |
| Databáze: | OpenAIRE |
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